박사,
Rutgers the State Univ. New Jersey Cook College ,
200710
석사,
고려대학교 식품공학과 (세부전공 : 식품가공 및 미생물),
199702
학사,
고려대학교 ,
199502
경력
교수,
상명대학교,
(2020.03~ )
조교수,
서울여자대학교,
(2014.09~2020.02)
연구교수,
고려대학교 ,
(2013.09~2014.08)
연구교수,
차의과학대학교,
(2011.08~2013.08)
Post-Doc.,
Rutgers University,
(2008.01~2011.07)
연구원(위촉),
한국식품연구원,
(1999.03~2001.12)
연구원(사원),
크라운제과,
(1996.12~1999.02)
논문
Nootkatone (NK), a grapefruit-derived aromatic compound, inhibited lipid accumulation by regulating JAK2-STAT signaling and antioxidant response in adipocyte,
Food Science and Biotechnology,
202402
Lactobacillus brevis-fermented gamma-aminobutyric acid ameliorates depression- and anxiety-like behaviors by activating the brain-derived neurotrophic factor-tropomyosin receptor kinase B signaling pathway ,
Journal of Agricultural and Food Chemistry,
202402
Protective effects of whey protein hydrolysate, treadmill exercise, and their combination against scopolamine-induced cognitive deficit in mice,
Foods,
202312
Neuroprotective effect of whey protein hydrolysate containing LDIQK on HT22 cells in hydrogen peroxide-induced oxidative stress,
Journal of Dairy Science,
202312
Enzyme Activity and Lipogenesis Inhibition by Feremented Grain Using Natural Enzymes,
Molecules,
202310
Schsandra chinensis-derived gomisin C suppresses lipid accumulation by JAK2-STAT signaling in adipocyte,
Food Science and Biotechnology,
202302
Dibenzoylmethane ameliorates adiposity-mediated neuroinflammatory response and inflammation-mediated neuronal cell death in mouse microglia and neuronal cells ,
Food Science and Biotechnology,
202301
Roles of anti- and pro-oxidant potential of cinnamic acid and phenylpropanoid derivatives in modulating growth of cultured cells,
Food Science and Biotechnology,
202203
Lactiplantibacillus plantarum K8-based paraprobiotics prevents obesity and obesity-induced inflammatory responses in high fat diet-fed mice,
Food Research International,
202203
Curcuma phaeocaulis Inhibits NLRP3 Inflammasome in Macrophages and Ameliorates Nanoparticle-Induced Airway Inflammation in Mice,
Molecules,
202203
Lactobacillus plantarum K8-based paraprobiotics suppress lipid accumulation during adipogenesis by the regulation of JAK/STAT and AMPK signaling pathways,
JOURNAL OF FUNCTIONAL FOODS,
202112
무증자 발아현미를 이용한 단양주와 이양주의 이화학적 특성,
한국식품과학회지,
202110
Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Models,
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,
202104
Anti-inflammatory action of herbal medicine comprised of Scutellaria baicalensis and Chrysanthemum morifolium.,
Bioscience Biotechnology Biochemistry,
202009
Brassinin, a brassica-derived phytochemical, regulates monocyte-to-macrophage differentiation and inflammatory responses in human monocytes and murine macrophages,
Journal of Pharmacy and Pharmacology,
202005
Enzymatic hydrolysis increases ginsenoside content in Korean red ginseng (Panax ginseng CA Meyer) and their biotransformation under hydrostatic pressure.,
Journal of Science of Food and Agriculture,
201912
Punicalagin, a Pomegranate-Derived Ellagitannin, Suppresses Obesity and Obesity-Induced Inflammatory Responses Via the Nrf2/Keap1 Signaling Pathway. ,
Molecular Nutrition and Food Research,
201911
Parthenolide inhibits lipid accumulation via activation of Nrf2/Keap1 signaling during adipocyte differentiation.,
Food Science and Biotechnology,
201909
Parthenolide, a feverfew-derived phytochemical, ameliorates obesity and obesity-induced inflammatory responses via the Nrf2/Keap1 pathway.,
Pharmacological Research,
201907
Brassinin, a phytoalexin in cruciferous vegetables, suppresses obesity-induced inflammatory responses through the Nrf2-HO-1 signaling pathway in an adipocyte-macrophage co-culture system.,
Phytotherapy Research,
201905
Red ginseng extract regulates differentiation of monocytes to macrophage and inflammatory signalings in human monocytes.,
Food Science and Biotehcnoogy,
201904
홍삼 비사포닌 분획의 단핵세포 분화와 염증반응에 대한 억제효과,
한국식품과학회지,
201902
Red ginseng-derived saponin fraction suppresses the obesity-induced inflammatory responses via Nrf2-HO-1 pathway in adipocyte-macrophage co-culture system. ,
Biomedicine and Pharmacotherapy,
201812
홍삼 사포닌 분획의 Nrf2 Keap1 신호전달체계 조절을 통한 지방축적 및 활성산소종 억제효과 ,
한국식품과학회지,
201812
Polygonatum sibiricum rhizome promotes sleep by regulating non-rapid eye movement and GABAergic/serotonergic receptors in rodent models.,
Biomedicine and Pharmacotherapy,
201809
Dibenzoylmethane, a Component of Licorice, Suppresses Monocyte-to-Macrophage Differentiation and Inflammatory Responses in Human Monocytes and Mouse Macrophages. ,
Biological and Pharmaceutical Bulletin,
201808
Romaine Lettuce/Skullcap Mixture Improves Sleep Behavior in Vertebrate Models. ,
Biological and Pharmaceutical Bulletin,
201808
Isolation of a sleep-promoting compound from Polygonatum sibiricum rhizome. ,
Food Science and Biotechnology,
201807
Dibenzoylmethane Suppresses Lipid Accumulation and Reactive Oxygen Species Production through Regulation of Nuclear Factor (Erythroid-Derived 2)-Like 2 and Insulin Signaling in Adipocytes. ,
Biological and Pharmaceutical Bulletin,
201805
Compound K Inhibits the Lipopolysaccharide-Induced Inflammatory Responses in Raw 264.7 Cell Line and Zebrafish.,
Applied Science,
201804
Isolation of a sleep-promoting compound from Polygonatum sibiricum rhizome. ,
Biomedicine and Pharmacotherapy,
201803
Nelumbo nucifera Seed Extract Promotes Sleep in Drosophila melanogaster. ,
Biological and Pharmaceutical Bulletin,
201803
Effects of processing parameters on the inactivation of Bacillus cereus spores on red pepper (Capsicum annum L.) flakes by microwave-combined cold plasma treatment.,
International Journal of Food Microbiology,
201712
Cactus cladodes (Opuntia humifusa) extract minimizes the effects of UV irradiation on keratinocytes and hairless mice.,
Pharmaceutical Biology,
201712
Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. ,
Biological and Pharmaceutical Bulletin,
201707
Enzyme hydrolysate of silk protein suppresses tert-butyl hydroperoxide-induced hepatotoxicity by enhancing antioxidant activity in rats.,
한국식품저장유통학회,
201707
실크 단백질 가수분해물의 간 손상에 대한 보호효과,
한국식품저장유통학회지,
201702
Protective Effect of Deer Bone Oil on Cartilage Destruction in Rats with Monosodium Iodoacetate (MIA)-Induced Osteoarthritis.,
Biological and Pharmaceutical Bulletin,
201612
Topical application of spent coffee ground extracts protects skin from ultraviolet B-induced photoaging in hairless mice.,
Photochemical Photobiological Sciences,
201606
Optimization of Extraction of Cycloalliin from Garlic (Allium sativum L.) by Using Principal Components Analysis. ,
Preventive Nutrition and Food Science,
201606
Deer bone oil extract suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 cells. ,
Biological and Pharmaceutical Bulletin,
201604
Cholecalciferol inhibits lipid accumulation by regulating early adipogenesis in cultured adipocytes and zebrafish. ,
Biochemical and Biophysical Research Communications,
201601
Hepatoprotective effects of soluble rice protein in primary hepatocytes and in mice.,
Journal of the Science of Food and Agriculture,
201601
Seapolynol and Dieckol Improve Insulin Sensitivity through the Regulation of the PI3K Pathway in C57BL/KsJ-db/db Mice. ,
Journal of Food Nutrition Research,
201512
Seapolynol Extracted from Ecklonia cava Inhibits Adipocyte Differentiation in Vitro and Decreases Fat Accumulation in Vivo. ,
Molecules,
201512
Spent coffee ground extract suppresses ultraviolet B-induced photoaging in hairless mice.,
Journal of Photochemistry and Photobiology B,
201512
Protective effects of germinated and fermented soybean extract against tert-butyl hydroperoxide-induced hepatotoxicity in HepG2 cells and in rats.,
Food and Function,
201511
Hematopoietic effect of deer antler extract fermented by Bacillus subtilis on murine marrow cells. ,
Nutrition Research and Practice,
201510
Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish.,
Food and Function ,
201508
Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell cycle arrest and AMPKa activation. ,
Molecular Nutrition and Food Research,
201508
Biotransformation of catechin and extraction of active polysaccharide from green tea leaves via simultaneous treatment with tannase and pectinase. ,
Journal of the Science of Food and Agricuture,
201508
Lipase-mediated lipid removal from propolis extract and its antiradical and antimicrobial activity. ,
Journal of the Science of Food and Agriculture,
201506
Effect of Porcine Placenta Extract from Subcritical Water Extraction on Photodamage in Human Keratinocytes.,
Korean Journal of Food Science of Animal Resources,
201504
The Culture Broth of Pediococcus pentosaceus T1 Inhibits Listeria Proliferation in Salmon Fillets and Controls Maturation of Kimchi.,
Food Technology and Biotechnology,
201503
Ellagic Acid Suppresses Lipid Accumulation by Suppressing Early Adipogenic Events and Cell Cycle Arrest. ,
Phytotherapy Research,
201503
Blockade of lipid accumulation by silibinin in adipocytes and zebrafish. ,
Chemico-Biological Interactions,
201502
Oleuropein Suppresses LPS-Induced Inflammatory Responses in RAW 264.7 Cell and Zebrafish.,
Journal of Agricultural and Food Chemistry,
201501
Gelidium elegans, an Edible Red Seaweed, and Hesperidin Inhibit Lipid Accumulation and Production of Reactive Oxygen Species and Reactive Nitrogen Species in 3T3-L1 and RAW264.7 Cells. ,
Phytotherapy Research,
201411
Differential activities of fungi-derived tannases on biotransformation and substrate inhibition in green extract. ,
Journal of Bioscience and Bioengineering,
201411
Radical-Scavenging Activities of Cactus Cladodes (Opuntia Humifusa Raf.) in a Submerged Culture. ,
Journal of Food Biochemistry,
201410
Enzymatic transformation of ginsenosides in Korean Red Ginseng (Panax Ginseng Meyer) extract prepared by Spezyme and Optidex. ,
Journal of Ginseng Research,
201410
Indole-3-carbinol, a vegetable phytochemical, inhibits adipogenesis by regulating cell cycle and AMPKα ,
Biochimie,
201409
Identification of an anti-listerial domain from Pediococcus pentosaceus T1 derived from Kimchi, a traditional fermented vegetable.,
Food Control,
201409
Effects of deer bone extract on the expression of pro-inflammatory cytokine and cartilage related genes in monosodium iodoacetate-induced osteoarthritic rats. ,
Bioscience, Biotechnology and Biochemistry ,
201406
Protective Effects of Ginseng Leaf Extract Using Enzymatic Extraction Against Oxidative Damage of UVA-Irradiated Human Keratinocytes. ,
Applied Biochemistry and Biotechnology,
201406
Baicalein inhibits lipid accumulation by regulating early adipogenesis and m-TOR signaling. ,
Food Chemical and Toxicology,
201405
Catechine biotransformation by tannase with sequential addition of substrate. ,
Process Biochemistry,
201402
패각칼슘입자크기에 따른 흡수율,
한국식품영양과학회지,
201312
Antioxidant activity and anti-adipogenic effects of wild herbs mainly cultivated in Korea. ,
Molecules ,
201310
Nano-calcium ameliorates ovariectomy-induced bone loss in female rats.,
Korean Journal of Food Science and Animal Resources,
201308
The Edible red Alga, Gracilaria verrucosa, Inhibits Lipid Accumulation and ROS Production, but Improves Glucose Uptake in 3T3-L1 Cells. ,
Phytotherapy Research,
201307
Grateloupia lanceolata (Okamura) Kawaguchi, the Edible Red Seaweed, Inhibits Lipid Accumulation and Reactive Oxygen Species Production During Differentiation in 3T3-L1 Cells. ,
Phytotherapy Research,
201305
PineXol®의 항산화 및 지방세포 분화 억제 효과,
한국식품과학회지,
201301
Extract from Edible Red Seaweed (Gelidium amansii) Inhibits Lipid Accumulation and ROS Production during Differentiation in 3T3-L1 Cells,
Preventive Nutrition and Food Science,
201206
Inhibition of Reactive Oxygen Species (ROS) and Nitric Oxide (NO) by Gelidium elegans Using Alternative Drying and Extraction Conditions in 3T3-L1 and RAW 264.7 Cells,
Preventive Nutrition and Food Science,
201206
오가피순 추출물의 항산화효과 및 아질산염 소거능,
한국식품영양과학회지,
201204
Pho85p-Pho80p phosphorylation of yeast Pah1p phosphatidate phosphatase regulates its activity, location, abundance, and function in lipid metabolism. ,
Journal of Biological Chemistry,
201203
Pycnogenol Inhibits Lipid Accumulation in 3T3-L-1 Adipocytes with the Modulation of Reactive Oxygen Species (ROS) Production Associated with Antioxidant Enzyme Responses.,
Phytotherapy Research,
201203
3T3-L1 세포분화중 지방축적 및 ROS 생성에 대한 자가시모자반 추출물의 효과.,
한국식품저장유통학회지,
201203
3T3-L1 지방세포내 ROS 생성에 대한 천년초 열수 및 에탄올 추출물의 항산화 효과. ,
한국식품저장유통학회지,
201203
Phosphatidate phosphatase plays role in zinc-mediated regulation of phospholipid synthesis in yeast.,
Journal of Biological Chemistry,
201201
Antioxidant and Anti-Adipogenic Effects of Ethanolic Extracts from Tartary and Common Buckwheats. ,
한국식품저장유통학회,
201201
Clinical and microbial evaluation of the effects on gingivitis of a mouth rinse containing an Enteromorpha linza extract,
Journal of Medicinal Food,
201111
Phosphorylation of Phosphatidate phosphatase regulates its membrane association and physiological functions in Saccharomyces cerevisiae.,
Journal of Biological Chemistry,
201101
Phosphorylation of yeast phosphatidylserine synthase by protein kinase A. ,
Journal of Biological Chemistry,
201004
Respiratory deficiency mediates the regulation of the CHO1-encoded phosphatidylserine synthase by mRNA stability in S. cerevisiae.,
Journal of Biological Chemistry,
200710
Regulation of the yeast EKI1-encoded ethanolamine kinase by inositol and choline. ,
Journal of Biological Chemistry,
200408
Regulation of phospholipids synthesis in the yeast cki1D eki1D mutant defective in the Kennedy pathway. ,
Journal of Biological Chemistry,
200403
국내산 녹용의 부위별 식품학적 성분 분석,
한국식품과학회지,
200301
천마의 식품학적 성분 분석 및 건조방법에 따른 특성 변화.,
한국식품과학회지,
200201
Rheological Characteristics of hot-water extract concentrates from AgastacherugosaO.Kuntze. ,
Food Science and Biotechnoogy,
200107
Angiotensin I-converting enzyme inhibitor from Grifola frondosa. ,
Food Research Interantional,
200103
Physicochemical Properties of Nagaimo, Ichoimo, Tsukuneimo. ,
Food Science and Biotechnology,
200101
지식재산
피부손상 방어복구 및 피부재생용 이너뷰티 건강식품 조성물 및 이를 포함하는 피부손상 방어복구 및 피부재생용 이너뷰티 건강식품 ,
최현선 강남길 김민하,
20230927
항산화용 이너뷰티 건강식품 조성물 및 이를 포함하는 항산화용 이너뷰티 건강식품,
최현선, 강남길, 김민하,
20230816
미립화된 유산균 사균체를 포함하는 비만 예방 및 치료용 조성물,
정대균, 김훈, 최현선,
20201028
학술발표
Fermented product containing GABA by Lactobacillus brevis ameliorates depression/anxiety-like behaviors in unpredictable chronic mild stress-induced mice by activating the BDNF signaling pathway,
한국식품영양과학회,
20231019
The effect of yeast hydrolysate and scercise on high-fat diet-induced obesityin C57BL/6J mice,
한국식품영양과학회,
20231019
Antioxidant and anti-adipogenic effects of edible plants,
한국식품과학회,
20230628
Physicochemical property and anti-inflammatory effect of five edible plants,
한국식품과학회,
20230628
Bioconversion of Nitrogen Oxide in Nitrate-containing Vegetables through the fermentation process of lactica acid bacteria ,
한국식품영양과학회,
20221020
Application of fermented Ulgari-Baedhu (Winter Grwon Cabbage) broth using lactic acid bacteria during the curing process of ground beef,
한국식품영양과학회,
20221020
Nootkatone suppreses the lipid accumuation by regulating JAK-STAT in murine adipocyte,
한국식품영양과학회,
20221020
Oenothera biennis sprout extract inhibited the adipogenic lipid storage by regulating JAK-STAT in murine adipocye,
한국식품영양과학회,
20221020
Effect of Gomisin C on inflammatory responses in human cell lines and C57BL/6 mice,
한국식품영양과학회,
20211028
Antioxidant and Anti-inflammatory effects of feremented Rhynchosia nulubilis extact,
한국식품영양과학회,
20211028
Lactic acid bacterial lysates ameliorates obesity and obesity-induced inflammatory responses via regulation of NF-kB and AMPKa in high fat-induced obse mice ,
한국식품영양과학회,
20211028
Lactic acid bacteria lysates suppress the lipid accumulation by regulating JAK-STAT and AMPKa signaling in murine adipocyte,
한국식품과학회,
20210709
LAB-Fermented Aronia Suppresses Obesity and Obesity-induced Neuroinflammation and Cognitive Deficit in C57BL/6J Mice,
한국식품영양과학회,
20201023
Effect of Gomisin C on Lipid Accumulation and Monocyte-to-macrophage Differentiation in Murine Adipocytes and Human Monocytes,
한국식품영양과학회,
20201023
LAB-Fermented Aronia Improves the Antioxidant Properties and Adipocity-induced Neuronal Cell Death,
한국식품영양과학회,
20201022
Lactobacillus-fermented gamma-aminobutyric acid (LB-GABA) improves sleep behaviors in invertebrate and vertebrate models,
한국식품영양과학회,
20201022
Punicalagin ameliorates obesity-induced inflammatory responses via Nrf2/KEAP1 signaling pathway in co-culture system and high-fat-diet fed mice.,
한국식품과학회,
20181024
Saponin fraction suppresses the obesity-induced inflammatory responses via Nrf2-Keap1 pathway in 3T3-L1 and RAW264.7 co-cultured system.,
한국식품과학회,
20181024
Parthenolide, a feverfew-derived compound, suppresses the obesity-induced inflammatory responses in co-culture system and high-fat diet-challenged C57BL/6J mice: Activation of Nrf2/Keap1 pathway.,
한국식품과학회,
20181024
Non-saponin fraction ameliorates obesity-induced inflammatory responses via Nrf2/KEAP pathway in macrophages and co-culture system.,
한국식품과학회,
20181024
Pathenolide suppresses lipid accumulation and adiposity-mediated inflammatory responses in adipocyte and co-cultured system.,
한국식품과학회,
20170622
Brassinin suppresses LPS-induced inflammatory responses and lipid accumulation in RAW264.7 and 3T3-L1 cells. ,
한국식품과학회,
20170622
Gomisin C suppresses lipid accumulation and oxidative stress by regulating Nrf2-Keap1 pathway in adipocyte.,
한국식품영양과학회,
20161101
Dibenzoylmethane suppresses lipid accumulation and oxidative stress by regulating Nrf2-Keap1 pathway in adipocyte.,
한국식품영양과학회,
20161101
Cholecalciferol inhibits lipid accumulation by regulating early adipogenesis in cultured adipocytes and zebrafish,
한국식품과학회,
20150604
Anti-inflammatory and Anti-osteoarthritic Activity of Deer Bone Oil Extract in Raw 264.7 Cell and Primary Cultured Rabbit Chondrocytes.,
한국식품과학회,
20140826
Effect of Energy Drink Ingredients on Behavor and Life-span in Invertebrate Model,
한국식품과학회,
20140826
Seanol®and its compound, Dieckol inhibit lipid accumulation during adipogenesis in 3T3-L1 cells.,
EB2013 American Society of Nutrition ,
20130408
Baicalein inhibits lipid accumulation through regulation of cell cycle and early adipogenesis in 3T3-L1 cells.,
EB2013 American Society of Nutrition,
20130408
Phosphorylation of Yeast Phosphatidate Phosphatase by Cyclin-dependent Kinase Pho85p. ,
EB2011 American Society of Biochemistry and Molecular Biology ASBMB 2011,
20110405
Identification of cyclin-dependent kinase phosphorylation sites in yeast phosphatidate phosphatase.,
ASBMB 2010,
20100405
Phosphorylation of yeast phosphatidylserine synthase by protein kinase A.,
ASBMB2009,
20090406
Respiratory deficiency mediates the regulation of CHO1-encodedphosphatidylserine synthase by mRNA stability in yeast. ,
Gordon Research Conference,
20070604
EKI1-dependent regulation of phospholipids synthesis by ASBMBmRNAstability,
ASBMB2006,
20060403
Regulation of phospholipids synthesis in the yeast cki1D eki1D mutant defective in the Kennedy pathway.,
ASBMB 2004,
20040405
수상
KoSFoST FSB 학술지 우수논문 심사위원,
한국식품과학회,
20230630
우수편집자상 Microbiology and Biotechnology letters,
한국미생물 생명공학회,
20230621
학술지 우수 논문심사위원 (FSB),
한국식품과학회,
20200702
우수편집자상 (MBL),
한국미생물. 생명공학회 ,
20190624
Young Scientist Presenter,
한국식품영양과학회,
20121031
ASBMB Travel Award,
ASBMB,
20110405
ASBMB Travel Award,
ASBMB,
20100405
ASBMB Travel Award,
ASBMB,
20090406
Graduate student prize in Food Science ,
George M. Carman,
20071203
Graduate student poster award,
Theobald Smith Society Meeting,
20060908
ASBMB Travel Award,
ASBMB( American Society of Biochemistry and Molecular Biology),
20040405
프로젝트
(주) 대상,
유글레나 유래 베타글루칸의 미세먼지 유도 기관지염에 대한 효과 검증,
(2023.08~2024.02)
(주) 바이오엑스,
미생물 배양/보전 및 분석 용역연구,
(2023.04~2023.09)
한국연구재단,
체내 산화질소 공급을 위한 유산균/채소기반 신바이오틱스 개발과 심혈관질환 타겟 발효소재 탐구 및 기작연구,
(2022.06~2025.02)
(주) 아모레 퍼시픽,
GABA소재의 긴장완화 기능성 POC 확보 연구,
(2022.06~2023.06)
(주) 아모레퍼시픽,
GABA를 이용한 수면효능연구,
(2019.10~2020.09)
피부생명공학센터(경희대),
유산균 복합물의 비만 및 비만관련 염증반응에 대한 효능검증,
(2019.09~2020.02)
한국연구재단,
발효공정을 이용한 식품생리활성소재의 비만관련 신경세포염증 및 인지기능저하에 대한 효과와 기작연구,
(2018.06~2022.05)
